Chemotherapy advances in head and neck oncology
β Scribed by Dr. William Liggett Jr; Arlene A. Forastiere
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 827 KB
- Volume
- 11
- Category
- Article
- ISSN
- 8756-0437
No coin nor oath required. For personal study only.
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## Abstract ## Background In an effort to optimize nonoperative therapy in patients with locoregionally advanced head and neck squamous cell cancer, the Southwest Oncology Group conducted a phase II trial combining 3βdrug taxaneβcontaining induction chemotherapy with accelerated fractionation/conc
Induction (proto) chemotherapy consisting of 3 courses of cisplatin and 120-hour 5-fluorouracil infusion was administered to 88 patients who had locally advanced, previously untreated head and neck cancer. The majority (81%) of these patients were classified as stage IV, and 17% had second primary c