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Chemosensitization of myeloma plasma cells by an antisense-mediated downregulation of Bcl-2 protein

✍ Scribed by van de Donk, N W C J; Kamphuis, M M J; van Dijk, M; Borst, H P E; Bloem, A C; Lokhorst, H M


Book ID
110055324
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
245 KB
Volume
17
Category
Article
ISSN
0887-6924

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## Abstract Our study was designed to investigate the role of the anti‐apoptotic proteins Bcl‐2 and Bcl‐xL in the chemoresistance of cells derived from malignant pleural mesothelioma. First, we determined the basal expression levels of Bcl‐2 and Bcl‐xL in mesothelioma cells and examined the effect