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Chemoselective synthesis of thieno[3,2-c][1,8]naphthyridin-4(5H)-ones by tandem cyclization

✍ Scribed by Krishna C. Majumdar; Rafique-ul-Islam

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
127 KB
Volume
18
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

A number of the thieno[3,2‐c][1,8]‐naphthyridin‐4(5__H__)‐ones are chemoselectively synthesized from 4‐(4′‐aryloxybut‐2′‐ynylthio)‐1‐phenyl‐1,8‐naphthyridin‐2(1__H__)‐ones in 82–90% yield by the formation of sulfoxide, followed by [2,3] and [3,3]sigmatropic rearrangement and an intramolecular Michael addition. Β© 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:87–92, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20234

πŸ“œ SIMILAR VOLUMES

Chemoselective Synthesis of Thieno[3,2-c
Chemoselective Synthesis of Thieno[3,2-c][1,8]naphthyridin-4(5H)-ones by Tandem Cyclization.
✍ Majumdar Krishna C. Majumdar Krishna C.; Rafique-ul-Islam Rafique-ul-Islam πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons βš– 24 KB πŸ‘ 1 views

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