A Convenient Synthesis of 4-Aryl-1,8-naphthyridin-2(1H)-ones by the Suzuki Coupling.
β Scribed by Hitoshi Ban; Masami Muraoka; Naohito Ohashi
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 129 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A number of the thieno[3,2β__c__][1,8]βnaphthyridinβ4(5__H__)βones are chemoselectively synthesized from 4β(4β²βaryloxybutβ2β²βynylthio)β1βphenylβ1,8βnaphthyridinβ2(1__H__)βones in 82β90% yield by the formation of sulfoxide, followed by [2,3] and [3,3]sigmatropic rearrangement and an intr