Chemoselective synthesis of 1-alkyl-4-(4-amino-2,6-dichlorophenoxy)-5-halopyridazin-6-ones
✍ Scribed by Deok-Heon Kweon; Ju-Wha Chung; Su-Dong Cho; Sung-Kyu Kim; Yong-Jin Yoon
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1998
- Tongue
- English
- Weight
- 196 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
Some 1‐alkyl‐4‐(4‐amino‐2,6‐dichlorophenoxy)‐5‐halopyridazin‐6‐ones were synthesized chemoselectively from 1‐alkyl‐4,5‐dihalopyridazin‐6‐ones and 4‐amino‐2,6‐dichlorophenol via a fluoride ion‐assisted reaction.
📜 SIMILAR VOLUMES
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## Abstract [4″‐^3^H]‐2‐(1‐[2″,6″‐Dichlorophenoxy]‐ethyl‐Δ^2^‐imidazoline) was prepared from [4‐^3^H]‐2,6‐dichlorophenol in two different ways. By reaction of 2,6‐dichlorophenol with 2‐(α‐chloroethyl)‐Δ^2^‐imidazoline, the radiochemical yield, at a specific activity of 173.9 mCi/mmole, was 12.8 %.