Chemoselective reductions of nitroarenes: bromoethanol-assisted phthalocyanatoiron/NaBH4 reductions

✍ Scribed by H.Scott Wilkinson; Gerald J Tanoury; Stephen A Wald; Chris H Senanayake

• Book ID: 104211464
• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 97 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)01920-1

✦ Synopsis

Porphyrinatoiron/NaBH 4 and a novel phthalocyanatoiron/NaBH 4 catalyst systems were investigated for the reductions of nitroarenes. The phthalocyanatoiron/NaBH 4 system was superior to the porphyrinatoiron/NaBH 4 system. The reductions were performed in good yields and excellent chemoselectivities. The rate of reduction by the PcFe/NaBH 4 system increased upon the addition of 2-bromoethanol.