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Chemoselective Acylation of Some Oxidofunctionalized Organolithium Compounds.

โœ Scribed by Miguel Yus; Joaquin Gomis


Publisher
John Wiley and Sons
Year
2003
Weight
127 KB
Volume
34
Category
Article
ISSN
0931-7597

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Chemoselective acylation of some oxidofu
โœ Miguel Yus; Joaquฤฑฬn Gomis ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 110 KB

Once oxidofunctionalised organolithium compounds 1 (easily prepared by reductive ring opening of isochroman and phthalan by DTBB-catalysed lithiation) were transmetallated with ZnBr 2 /CuCNโ€ข2LiCl and reacted successively with a carboxylic acid anhydride and an acyl chloride in THF at 08C, the corres