Chemokine Receptors as Drug Targets (Methods and Principles in Medicinal Chemistry)

✍ Scribed by Martine J. Smit, Sergio A. Lira, Rob Leurs, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

Publisher: Wiley-VCH
Year: 2010
Tongue: English
Leaves: 396
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Opening with a general introduction on chemokine function and chemokine receptor biology, the handbook goes on to cover the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including HIV/AIDS. The second half of the book systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners. Contributions in the first part of the book are mainly from academia, whereas the second part contains up-to-date reports from the pharmaceutical industry.

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