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Chemoenzymatic synthesis of orthogonally protected (3R,4R)- and (3S,4S)-trans-3-amino-4-hydroxypyrrolidines

✍ Scribed by Rodríguez-Rodríguez, Jesús A.; Quijada, F. Javier; Brieva, Rosario; Rebolledo, Francisca; Gotor, Vicente


Book ID
120360864
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
610 KB
Volume
69
Category
Article
ISSN
0040-4020

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Synthesis of (2S,3R)-3-amino-2-hydroxyde
✍ Arounarith Tuch; Michèle Sanière; Yves Le Merrer; Jean-Claude Depezay 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 528 KB

Taking advantage of the high functionality of an enantiopure protected syn-2R-amino-l,3,4-triol derivative, easily available on a multigram scale from Disoascorbic acid, several biologically active compounds have been synthesized such as the (2S,3R)-3-amino-2-hydroxydecanoic acid (AHDA), the N-termi