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Chemoenzymatic Synthesis of Neuraminic Acid Containing C -Glycoside Polymers

✍ Scribed by Wang, Qun; Dordick, Jonathan S.; Linhardt, Robert J.


Book ID
127374746
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
60 KB
Volume
5
Category
Article
ISSN
1523-7060

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A chemoenzymatic approach was developed to prepare sucrose-containing aromatic polymers. The protease from Bacillus licheniformis catalyzed the transesterification of sucrose with a diester of terephthalic acid in pyridine to give the mono-and diester products. At 45Β°C, >70% of sucrose was consumed