𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Chemoenzymatic synthesis of macrocyclic polyamines

✍ Scribed by Wei Lu; Charles J. Sih


Book ID
104261737
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
189 KB
Volume
40
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


Β±)-Azemacrolides were synthesized via lipase-catslyzed intmmolccular cyclization of (~-)-hydroxy-azaesters. Further, the size of the macrocyclic lactones formed could be altered by the substituent on the nitrogen atom. This allows one to prepare a combinatorial library of azamacrolides from a small number of hydroxy-azaesters using this biocatalytic approach.


πŸ“œ SIMILAR VOLUMES


Preparation of C-alkylated macrocyclic p
✍ Iwao Tabushi; Yoichi Taniguchi; Hidefumi Kato πŸ“‚ Article πŸ“… 1977 πŸ› Elsevier Science 🌐 French βš– 170 KB

Macrocyclic polyamines have attracted increasing attention because of their unique property to form very stable chelates with various heavy metal ions l-6) .