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Chemoenzymatic synthesis of glucose fatty esters

✍ Scribed by Ines Redmann; Michel Pina; Bernard Guyot; Pierre Blaise; Marie Farines; Jean Graille


Book ID
108309654
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
442 KB
Volume
300
Category
Article
ISSN
0008-6215

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Chemoenzymatic Synthesis of Glucose Fatty Esters. -D-Glucose fatty esters at C-6 are obtained by chemoenzymatic esterification of Ξ±-Dglucofuranose (I) followed by hydrolysis of the cyclohexylidene protecting group. The kinetic of the reaction is studied for several fatty acids. -(REDMANN, I.;

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A concise, polymer-supported solution synthesis of 6-O-(g-aminobutyryl)-D-glucose has been achieved. Glucose was attached to polyethylene glycol monomethyl ether (MPEG) through an a,a%-dioxyxylyl diether linker, and, subsequently, the HO-6 hydroxyl of the glucose was regioselectively esterified with