Chemoenzymatic Synthesis of Enantiomerically Pure (2S,3R,4S)-4-Hydroxyisoleucine, an Insulinotropic Amino Acid Isolated from Fenugreek Seeds
✍ Scribed by Valérie Rolland-Fulcrand; Marc Rolland; Marie-Louise Roumestant; Jean Martinez
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 123 KB
- Volume
- 2004
- Category
- Article
- ISSN
- 1434-193X
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Synthesis of (2S\*,4R\*,5S\*)-Piperidinetricarboxylic Acid, a Non-Proteinogenic Amino Acid Isolated from Clitocybe Acromelalga. -The title compound (IX) is synthesized from the pyridine triester (VI) by stepwise hydrogenation of the pyridine ring with intermediate cis-trans isomerization. -(HASHIMO