A Practical Synthesis of (2S,3R,4S)-4-Hydroxyisoleucine, A Potent Insulinotropic α-Amino Acid from Fenugreek

Chemoenzymatic Synthesis of Enantiomeric

Chemoenzymatic Synthesis of Enantiomerically Pure (2S,3R,4S)-4-Hydroxyisoleucine, an Insulinotropic Amino Acid Isolated from Fenugreek Seeds

✍ Valérie Rolland-Fulcrand; Marc Rolland; Marie-Louise Roumestant; Jean Martinez 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB 👁 1 views

A Practical and Efficient Total Synthesi

A Practical and Efficient Total Synthesis of Potent Insulinotropic (2S,3R,4S)-4-Hydroxyisoleucine through a Chiral N-Protected γ-Keto-α-aminoester

✍ Sandra De Lamo Marin; Cédric Catala; Sreekantha Ratna Kumar; Alain Valleix; Alai 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB 👁 1 views

## Abstract (2__S__,3__R__,4__S__)‐4‐Hydroxyisoleucine, which exhibits remarkable insulinotropic activity, is expected to be a potent drug to treat type II diabetes. We propose herein a four‐step synthesis of the enantiopure natural product on the basis of successive Mannich condensation, catalytic

A Practical Synthesis of (2S, 3R)-3-Amin

A Practical Synthesis of (2S, 3R)-3-Amino-2-methylpentanoic Acid from L-Aspartic Acid

✍ Charles W. Jefford; James McNulty 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 German ⚖ 366 KB

The First Enantioselective Synthesis of

The First Enantioselective Synthesis of the Amino Acid (2S,3S,4R)-γ-Hydroxyisoleucine (V) Using a Palladium(II) Catalyzed 3,3-Sigmatropic Rearrangement.

✍ Andrew G. Jamieson; Andrew Sutherland; Christine L. Willis 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 113 KB 👁 1 views

ChemInform Abstract: Synthesis of (2S,3R

ChemInform Abstract: Synthesis of (2S,3R)-3-Amino-2-hydroxydecanoic Acid (VII) and (3R,4R)- 3-Amino-4-hydroxyazepane (XII) from D-Isoascorbic Acid.

✍ A. TUCH; M. SANIERE; Y. LE MERRER; J.-C. DEPEZAY 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: A Concise Diastereo

ChemInform Abstract: A Concise Diastereoselective Synthesis of (2S,3S,4R)-3,4-Dihydroxyglutamic Acid.

✍ Makoto Oba; Shinichi Koguchi; Kozaburo Nishiyama 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v