✦ LIBER ✦

Chemocontrolled reduction of aromatic α-ketoesters by NaBH4: Selective synthesis of α-hydroxy esters or 1,2-diols

✍ Scribed by Vincent Dalla; Philippe Cotelle; Jean Pierre Catteau

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 261 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)00154-8

No coin nor oath required. For personal study only.

✦ Synopsis

ot-hydroxyesters 5a.g or diols 6a.g have been obtained in high yields by reduction of aromatic ot-ketoesters 4 once or twice respectively by using NaBH4 as the reducer under suitable conditions. The use of a solvent that does not interact with the reagent allowed the double reduction to occur with only a slight excess of borohydride in very mild conditions.

📜 SIMILAR VOLUMES

ChemInform Abstract: Chemocontrolled Red

ChemInform Abstract: Chemocontrolled Reduction of Aromatic α-Ketoesters by NaBH4: Selective Synthesis of α-Hydroxy Esters or 1,2-Diols.

✍ V. DALLA; P. COTELLE; J. P. CATTEAU 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Reductions of α,β-Unsaturated Ketones by

Reductions of α,β-Unsaturated Ketones by NaBH4 or NaBH4 + CoCl2: Selectivity Control by Water or by Aqueous Micellar Solutions

✍ Andrea Aramini; Lucia Brinchi; Raimondo Germani; Gianfranco Savelli 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 1 views

Operationally simple and environmentally benign procedures have been developed to selectively reduce different α,βunsaturated ketones, 4,4-dimethylcyclohex-2-ene-1-one (1), isophorone (2), benzylideneacetone (3), chalcone (4) by NaBH 4 or by the system NaBH 4 + CoCl 2 . Alternative reaction media to

Enantioselective Reduction of α-Keto Est

Enantioselective Reduction of α-Keto Esters to 1,2-Diols Using the NaBH4/Me3SiCl System Catalyzed by Polymer-Supported Chiral Sulfonamide.

✍ Guang-yin Wang; Jian-bing Hu; Gang Zhao 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 111 KB 👁 1 views

Enantiospecific synthesis of optically p

Enantiospecific synthesis of optically pure (3s)-hydroxy esters by the stereocontrolled yeast reduction of α-sulfenyl-β-ketoesters

✍ Tamotsu Fujisawa; Toshiyuki Itoh; Toshio Sato 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 291 KB

Stereocontrol in Baker's yedst reduction of B-ketoesters was sucoessfutly achieved by introducing the sulfenyl guu>up at cl-position of the esters to afford opticalZy pure íS)-& hydmxy esters.

Direct Reductive Amination and Selective

Direct Reductive Amination and Selective 1,2-Reduction of α,β-Unsaturated Aldehydes and Ketones by NaBH4 Using H3PW12O40 as Catalyst.

✍ Akbar Heydari; Samad Khaksar; Jafar Akbari; Maryam Esfandyari; Mehrdad Pourayoub 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

ChemInform Abstract: Selective Reduction

ChemInform Abstract: Selective Reductions of Substituted α-(1,2,4-Triazol-1-yl)chalcones with NaBH4 and Al-Isopropoxide: Synthesis of Substituted (.+-.)α-(4-Chlorophenyl)-β- (phenylmethylene)-1H-1,2,4-triazole-1-ethanols Having Potential Bacteriostatic and Argo-Based Fungicidal Activity.

✍ Vinod Rama Uchil; Vidya Joshi 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v