## Abstract (3,4‐^13^C~2~)‐L‐proline and (^15^N)‐L‐proline were prepared from the correspondingly labeled L‐glumatic acids via a single scheme in high yield and on a gram scale. The synthetic route is based on the ring closure of L‐glutamic acid to L‐5‐oxoproline and the selective reduction of the
Chemo-enzymatic synthesis of specifically stable-isotope labelledL-glutamic acid and 2-oxoglutaric acid
✍ Scribed by J. J. Cappon; J. Baart; G. A. M. van der Walk; J. Raap; J. Lugtenburg
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 996 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0165-0513
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