ChemInform Abstract: α-Alkoxystannyl Ethers in Organic Synthesis: Synthesis of Functionalized γ-Butyrolactones.
✍ Scribed by P. GILBERT; M. L. LEWIS; P. QUAYLE; Y. ZHAO; K. MILLS
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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Preparation of α-Methylene-γ-butyrolactones with Difluoromethylene Functionalities. -The key to the preparation of title compounds such as (XII), of interest as pharmaceutical drugs, is the regioselective reduction of the ester group of compound (VI) activated with a difluoromethylene unit to give