ChemInform Abstract: Use of Pentafluorophenyl Esters for One-Pot Protection/Activation of Amino and Thiol Carboxylic Acids.
β Scribed by L. M. GAYO; M. J. SUTO
- Book ID
- 112038536
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
## Abstract Protection of the amino group and activation of the carboxylic acid groups are the most important steps associated with any peptide synthesis protocol; hence, a oneβpot process to achieve these is highly desirable. A possible strategy is to use pentafluorophenyl carbonates to simultaneo
One-Pot Neat Reactions of Carboxylic Esters and Alkylenediamines for Efficient Preparation of N-Acylalkylenediamines. -A convenient and efficient monoamidation, even for the preparation of tertiary amides, by reaction of esters (I) and (V) with diamines (II) and (VI) is described. The resulting amid