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ChemInform Abstract: One-Pot Neat Reactions of Carboxylic Esters and Alkylenediamines for Efficient Preparation of N-Acylalkylenediamines.

✍ Scribed by Wen-Chih Chou; Chang-Wei Tan; Shyh-Fong Chen; Hao Ku

Book ID: 101883391
Publisher: John Wiley and Sons
Year: 2010
Weight: 30 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199924065

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✦ Synopsis

One-Pot Neat Reactions of Carboxylic Esters and Alkylenediamines for Efficient Preparation of N-Acylalkylenediamines. -A convenient and efficient monoamidation, even for the preparation of tertiary amides, by reaction of esters (I) and (V) with diamines (II) and (VI) is described. The resulting amides are useful building blocks for the synthesis of antihypertensive agents. -(CHOU, WEN-CHIH; TAN, CHANG-WEI; CHEN, SHYH-FONG;

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