✦ LIBER ✦

ChemInform Abstract: Unexpected Formation of O-Methoxycarbonyl Cyanohydrin Showing Potential as a Protective Group of Ketones.

✍ Scribed by Donald Poirier; David Berthiaume; Roch P. Boivin

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199949070

No coin nor oath required. For personal study only.

✦ Synopsis

Unexpected Formation of O-Methoxycarbonyl Cyanohydrin Showing Potential as a Protective Group of Ketones.

-Methyl cyanoformate (II) readily reacts with ketones (I) and (IV) in the presence of an amine base to yield O-methoxycarbonyl cyanohydrins. As easy hydrolysis of these cyanohydrins [cf. (V)] with catalytic potassium carbonate is achieved, this functional group shows interesting potential in protecting group chemistry.

📜 SIMILAR VOLUMES

ChemInform Abstract: O-Methoxycarbonyl C

ChemInform Abstract: O-Methoxycarbonyl Cyanohydrin as a New Protective Group for Carbonyls.

✍ David Berthiaume; Donald Poirier 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 2 views

ChemInform Abstract: The Reaction of o-A

ChemInform Abstract: The Reaction of o-Amino Aryl Carboxylic Acids with Grignard Reagents. The Unusual Effect of the N-Protecting Group on Aryl Ketone Formation.

✍ Puwen Zhang; Eugene A. Terefenko; Joseph Slavin 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Acetyl Chloride—Met

ChemInform Abstract: Acetyl Chloride—Methanol as a Convenient Reagent for: A) Quantitative Formation of Amine Hydrochlorides, B) Carboxylate Ester Formation, C) Mild Removal of N-Boc-Protective Group.

✍ AYELET NUDELMAN; Y. BECHOR; E. FALB; B. FISCHER; B. A. WEXLER; ABRAHAM NUDELMAN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

ChemInform Abstract: KF/Al2O3 and PEG-40

ChemInform Abstract: KF/Al2O3 and PEG-400 as a Recyclable Medium for the Selective α-Selenation of Aldehydes and Ketones. Preparation of Potential Antimicrobial Agents.

✍ Francine Novack Victoria; Catia S. Radatz; Maraisa Sachini; Raquel G. Jacob; Gel 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

ChemInform Abstract: Acetyl Bromide—Alco

ChemInform Abstract: Acetyl Bromide—Alcohols as Convenient Reaction Systems for: a) Removal of N-tert-Boc, N-Cbz and N-Ac Protective Groups b) Esterifications and Transesterifications c) Debenzylation of Aryl-O-benzyl Ethers.

✍ Anat Lesk; Abraham Nudelman 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views