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ChemInform Abstract: Total Synthesis of the Marine Natural Product 7-Deoxy-okadaic Acid (I): A Potent Inhibitor of Serine/Threonine-Specific Protein Phosphatases.

✍ Scribed by Amy B. Dounay; Rebecca A. Urbanek; Steven F. Sabes; Craig J. Forsyth

Publisher: John Wiley and Sons
Year: 2010
Weight: 27 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199950232

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Abstract

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Total Synthesis of the Marine Natural Pr

Total Synthesis of the Marine Natural Product 7-Deoxy-okadaic Acid: A Potent Inhibitor of Serine/Threonine-Specific Protein Phosphatases

✍ Amy B. Dounay; Rebecca A. Urbanek; Steven F. Sabes; Craig J. Forsyth 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB 👁 1 views

ChemInform Abstract: Total Synthesis of

ChemInform Abstract: Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor.

✍ J. E. II SHEPPECK; W. LIU; A. R. CHAMBERLIN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 2 views

Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor. -A convergent, asymmetric synthesis of the title compound (I) with an overall yield of 1.5% and a longest sequence of 19 steps is described by use of the readily available terpenes citronellene and geraniol epoxide for t