The Total Synthesis of Spirotryprostatin A. -Key step in the synthesis of the title alkaloid (XI) which is found in the fermentation broth of Aspergillus fumigatus and which manifests cell cycle inhibition at the G2/M phase, is the rearrangement of a bromohydrin prepared in situ from Ξ²-carboline de
β¦ LIBER β¦
ChemInform Abstract: Total Synthesis of Spirotryprostatin A, Leading to the Discovery of Some Biologically Promising Analogues.
β Scribed by Scott Edmondson; Samuel J. Danishefsky; Laura Sepp-Lorenzino; Neal Rosen
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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