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ChemInform Abstract: Total Synthesis of Rhizoferrin, an Iron Chelator.

✍ Scribed by R. J. BERGERON; M. XIN; R. E. SMITH; M. WOLLENWEBER; J. S. MCMANIS; C. LUDIN; K. A. ABBOUD


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Total Synthesis of Rhizoferrin, an Iron Chelator.

-The key steps in the synthesis of the title compound (VI), which is isolated from Rhizopus microsporus var. rhizopodiformis, are separation of the enantiomers of the acid (II) by formation of the (-)-brucine salts and condensation of the (R)-acid with the amine (III). -(BERGERON, R.


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