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ChemInform Abstract: An Expedient Total Synthesis of (.+-.)-Caparratriene.

โœ Scribed by James R. Vyvyan; Emily A. Peterson; Mari L. Stephan


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: First Total Synthes
โœ J. LI; Z. LIU; J. LAN; Y. LI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 2 views

First Total Synthesis of (+)-Caparratriene. -The title compound (V), a new sesquiterpene hydrocarbon with significant growth-inhibitory activity against CEM leukemia cells, is synthesized from commercially available citronellal (I) via three steps in an overall yield of 18%. Coupling reagent (II) i