𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Total Synthesis of Microtubule-Stabilizing Agent (-)-Laulimalide.

✍ Scribed by Arun K. Ghosh; Yong Wang; Joseph T. Kim

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
33
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Grubbs' RCM in the Total Synthesis of th
Grubbs' RCM in the Total Synthesis of the Microtubule Stabilizing Drug Laulimalide
✍ Johann Mulzer; Elisabeth Γ–hler; Valentinβ€…S. Enev; Martin Hanbauer πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 227 KB πŸ‘ 1 views

Two independent syntheses of the microtubule stabilizing antitumor agent laulimalide are described, which mainly differ with respect to the macrocyclization step. The first synthesis employs a StillΒ±Gennari olefination and the second one an Alexakis-type, allylsilane/acetal addition to close the fin