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ChemInform Abstract: Total Synthesis of Cytosporone B (IV).

✍ Scribed by He Huang; Lei Zhang; Xiaodong Zhang; Xun Ji; Xiao Ding; Xu Shen; Hualiang Jiang; Hong Liu


Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
41
Category
Article
ISSN
0931-7597

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Total Synthesis of Cytosporone B
✍ He Huang; Lei Zhang; Xiaodong Zhang; Xun Ji; Xiao Ding; Xu Shen; Hualiang Jiang; πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 57 KB

## Abstract The total synthesis of Cytosporone B, a naturally occurring agonist for Nur77, has been accomplished. The key steps are the sequential Grignard reaction and Lemieux‐van Rudloff oxidation followed by a deprotection of the methyl aromatic ether to phenol and subsequent Friedel‐Crafts acyl