ChemInform Abstract: Total Synthesis of Cryptophycins and Their 16-(3-Phenylacryloyl) Derivatives.
β Scribed by R. REJ; D. NGUYEN; B. GO; S. FORTIN; J.-F. LAVALLEE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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A Novel Approach for Total Synthesis of Cryptophycins via Asymmetric Crotylboration Protocol. -Crotylboration of aldehyde (I) with the Ξ±-pinene-derived boron reagent (II) provides the optically pure alcohol (IV) after oxidative work-up. Compound (IV) is linearly converted to the fragment A (V) of th
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