ChemInform Abstract: Facile Total Synthe
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Naoki Yamazaki; Toshimasa Ito; Chihiro Kibayashi
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Article
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2010
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John Wiley and Sons
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Facile Total Synthesis of (ยฑ)-Adalinine. -Allylation of cyclic N-acyl-N,O-acetals using a combination of allylsilane and Lewis acid provides a useful construction of 6,6-disubstituted 2-piperidones. Compound (VIII) can be readily converted to the ladybird alkaloid (X) mentioned in the title. -(YAMA