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ChemInform Abstract: Three Stereoisomers of a Novel and Selective μ-Opioid Analgesic.

✍ Scribed by S. IANELLI; M. NARDELLI; C. FRAIRE; G. GRANCINI; M. NAPOLETANO; F. SANTANGELO

Book ID
112024937
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Syntheses of Novel
ChemInform Abstract: Syntheses of Novel Pyrazolomorphinans and Their Binding to μ- and χ-Opioid-receptors.
✍ I. STROETMANN; G. SEITZ; K. T. WANNER; G. HOEFNER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Syntheses of Novel Pyrazolomorphinans and Their Binding to µand χ-Opioid-receptors. -A number of novel pyrazolomorphinans [cf. (V)/(VI)] are synthesized by reaction of the enolic morphinan diketones (III) with hydrazines and evaluated for their affinity at µ and χ-opioid receptors in radioligand bi