ChemInform Abstract: Three Component Reaction of Arynes with Cyclic Ethers and Active Methines: Synthesis of ω-Trichloroalkyl Phenyl Ethers.
✍ Scribed by Kentaro Okuma; Yuta Fukuzaki; Akiho Nojima; Ayumi Sou; Haruna Hino; Nahoko Matsunaga; Noriyoshi Nagahora; Kosei Shioji; Yoshinobu Yokomori
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 37 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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The reaction of benzenediazonium carboxylate with chloroform in refluxing tetrahydrofuran afforded 5,5,5-trichloropentyl phenyl ether in 61% yield along with benzoic acid (7%). When dichloroacetonitrile was used as a reactant, 5,5-dichloro-5-cyanopentyl phenyl ether was obtained in 65% yield. Reacti
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