Synthesis of Enantiomerically Pure Mono-, Di-, and Trisubstituted 2-Sulfinylbuta-1,3-dienes, via Ξ²-Hydroxy Selenides. -While deoxygenation of the epoxide (III) results in the exclusive formation of the sulfide (IV), elimination of the hydroxy selenides ( VI) according to the methods of Krief and Re
ChemInform Abstract: The Preparation of Mono-, 1,1-Di-, trans-1,2-Di- and Trisubstituted Ethylenes by Benzotriazole Methodology
β Scribed by Alan R. Katritzky; Dorin Toader
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 24 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Sulcatol (VIII) and three of its enantiomeric fluoro analogues (XI) are prepared in five steps and with good overall yields, starting from nearly equimolar mixtures of C-3 epimers of sulfoxides (I), (IX), (X), and the known trifluoro derivative. Reduction of the sulfoxides to the corresponding Ξ²-hyd
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