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ChemInform Abstract: The First Direct Synthesis of Pterocarpans via Aldol Condensation of Phenylacetates with Benzaldehydes.

โœ Scribed by T. G. VAN AARDT; P. S. VAN HEERDEN; D. FERREIRA


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: The Direct Synthesi
โœ M. VERSTEEG; B. C. B. BEZUIDENHOUDT; D. FERREIRA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 35 KB ๐Ÿ‘ 1 views

The Direct Synthesis of Isoflavans via ฮฑ-Alkylation of Phenylacetates. -Alkylation of phenylacetates (I) with Mom-protected o-hydroxybenzyl bromides [cf. (II)] using lithium isopropylcyclohexylamide in HMPA as base affords 2,3-diphenylpropanoates (III). They can be easily converted to isoflavans (V