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ChemInform Abstract: The Facile Synthesis of a Series of Tryptophan Derivatives.

โœ Scribed by Georg Blaser; John M. Sanderson; Andrei S. Batsanov; Judith A. K. Howard

Publisher
John Wiley and Sons
Year
2008
Weight
33 KB
Volume
39
Category
Article
ISSN
0931-7597

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Scandium-Mediated Opening of Aziridine Carboxylates: A Facile Synthesis of Aryl-Substituted Tryptophans. -Indoles (I) react with enantiopure N-protected aziridines (II) derived from L-serine in the presence of stoichiometric amounts of scandium triflate. Aryl-substituted and -protected tryptophans