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ChemInform Abstract: The Facile Syntheses of 2,3-Dihydro-1H-1,5-benzodiazepines and Their Ribofuranosides.

✍ Scribed by Renuka Jain; Tripti Yadav; Manoj Kumar; Ashok K. Yadav


Publisher
John Wiley and Sons
Year
2010
Weight
47 KB
Volume
41
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

A one‐pot procedure provides access to dihydrobenzodiazepines, e.g. (III), containing heterocyclic moieties or fused and spiro derivatives (VII) and (X) at ambient temperature in environmentally benign ionic liquids.


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## 12 -132 2,3-Dihydro-1H-1,5-benzodiazepines: A Conversion of Thiolactams to Amidines. -Benzodiazepinone derivatives (I) are transformed into the corresponding thiolactams (II), which can be converted to a new series of diversely substituted amidines [cf. (IV), (V)]. Ammonia, primary amines and h