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ChemInform Abstract: The Discovery of Substituted 4-(3-Hydroxyanilino)-quinolines as Potent RET Kinase Inhibitors.

✍ Scribed by R. Graham Robinett; Alex J. Freemerman; Michael A. Skinner; Lisa Shewchuk; Karen Lackey

Publisher: John Wiley and Sons
Year: 2008
Weight: 21 KB
Volume: 39
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200807215

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Novel Series of O-Substituted 8-Quinolines and 4-Benzothiazoles as Potent Antagonists of the Bradykinin B 2 Receptors. -The synthesized title series of 8-quinolines (VIII) and 4-benzothiazoles (IX) are investigated for the desired bradykinin B 2 receptor antagonistic activity. The 8-quinoline series