ChemInform Abstract: Tetrahydro-2H-1,3,5-thiadiazine-5-(4-pyridylcarboxamide)-2-thione Derivatives as Prodrugs for Isoniazid; Synthesis, Investigations, and in vitro Antituberculous Activity.
β Scribed by T. Aboul-Fadl; K. Hassanin
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Tetrahydro-2H-1,3,5-thiadiazine-5-(4-pyridylcarboxamide)-2-thione Derivatives as Prodrugs for Isoniazid; Synthesis, Investigations, and in vitro Antituberculous Activity.
-The title compounds (V) (5 examples) exhibit higher lipophilicity and higher antitubercular activity compared to the parent drug isoniazid (IV). -(ABOUL-FADL, T.; HASSANIN, K.;
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