ChemInform Abstract: Synthesis of (Z)-1-Benzylidene-3-(1H-indol-1-yl)-1H-indene-2,2(3H)-dicarbonitriles via Three-Component Reaction of 2-Alkynylbenzaldehyde, Malononitrile, and Indole.
β Scribed by Guanyingsheng Qiu; Qiuping Ding; Yiyuan Peng; Jie Wu
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 20 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
The reaction proceeds highly selectively and might involve tandem condensation, nucleophilic addition and intramolecular 5βexoβcyclization.
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Library Construction of 1-(1H-Imidazol-1-yl)-1,2-dihydroisoquinolines via Three-Component Reaction of 2-Alkynylbenzaldehyde, Amine, and Imidazole. -A variety of anilines, substituted alkynylbenzaldehydes and imidazoles can be applied. No reaction takes place when a nonaromatic (benzyl) amine is used
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