ChemInform Abstract: Synthesis of Tricyclopolyprenols via a Radical Addition and a Stereoselective Elimination. Part 1. Methodology.

✍ Scribed by T. JENN; D. HEISSLER

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 40 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199815197

✦ Synopsis

Synthesis of Tricyclopolyprenols via a Radical Addition and a Stereoselective Elimination. Part 1. Methodology.

-Based on smooth radical addition of the alkenes (III) to the iodide (II) without radical rearrangement, stereoselective elimination of H 2 O from the activated alcohols (V) and (IX), and easy transformation of the electron-withdrawing groups (CO-O-Et, CN) into a methyl group, it is assumed that these reactions can be applied successfully to the synthesis of tricyclopolyprenols. -(JENN, T.;