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ChemInform Abstract: Synthesis of the Spore Photoproduct.

โœ Scribed by R. NICEWONGER; T. P. BEGLEY


Book ID
101844652
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
28
Category
Article
ISSN
0931-7597

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The spore photoproduct was synthesized in seven steps from dihydrothymine and 5-formyluracil using a mixed Aldol coupling as the key bond forming step.

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## Abstract Investigation of the DNA repair process performed by the spore photoproduct (SP) lyase repair enzyme is strongly hampered by the lack of defined substrates needed for detailed enzymatic studies. The problem is particularly severe because the repair enzyme belongs to the class of strongl