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ChemInform Abstract: Synthesis of the Polycyclopropane Antibiotic FR-900848 via the Horeau Gambit.

โœ Scribed by J. R. FALCK; B. MEKONNEN; J. YU; J.-Y. LAI

Book ID
112038383
Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Total Synthesis of
ChemInform Abstract: Total Synthesis of the Pentacyclopropane Antifungal Agent FR-900848.
โœ A. G. M. BARRETT; K. KASDORF ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 26 KB ๐Ÿ‘ 2 views

Total Synthesis of the Pentacyclopropane Antifungal Agent FR-900848. -Starting with asymmetric cyclopropanation reactions the corresponding fatty acid is built up. It is coupled with the nucleoside amine to yield the title compound (I), identical with the natural product. -(BARRETT, A.