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ChemInform Abstract: Synthesis of the Melanoma-Associated Ganglioside 9-O-Acetyl GD3 Through Regioselective Enzymatic Acetylation of GD3 Using Subtilisin.

โœ Scribed by S. TAKAYAMA; P. O. LIVINGSTON; C.-H. WONG

Book ID
101843058
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
28
Category
Article
ISSN
0931-7597

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Synthesis of the melanoma-associated gan
Synthesis of the melanoma-associated ganglioside 9-O-acetyl GD3 through regioselective enzymatic acetylation of GD3 using subtilisin
โœ Shuichi Takayama; Philip O Livingston; Chi-Huey Wong ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 208 KB

The melanoma-associated disialoganglioside 9-O-acetyl GD3 has been synthesized for the first time through regioselective enzymatic acetylation of GD3 using subtilisin as the biocatalyst and vinyl acetate as the acetyl donor.