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ChemInform Abstract: Synthesis of the Bifunctional Chelating Agent 6-(4-Aminobenzyl) -1,4,8,11-tetraazacyclotetradecane-N,N′,N′′,N′′′-tetraacetic Acid (H2NBn-TETA).

✍ Scribed by P. MOREAU; M. TINKL; M. TSUKAZAKI; P. S. BURY; E. J. GRIFFEN; V. SNIECKUS; ET AL. ET AL.

Publisher: John Wiley and Sons
Year: 2010
Weight: 36 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199802171

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✦ Synopsis

Synthesis of the Bifunctional Chelating Agent 6-(4-Aminobenzyl) -1,4,8,11-tetraazacyclotetradecane-N,N',N",N"'-tetraacetic Acid (H 2 NBn-TETA). -An improved procedure for the synthesis of the azamacrocyclic ligand (VII), used as a radionuclide carrier in cancer chemotherapy, is reported. Additionally, its complete characterization and purification is described for the first time.

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