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ChemInform Abstract: Synthesis of Tetrasubstituted Alkenes by Stereo- and Regioselective Stannyllithiation of Diarylacetylenes.

โœ Scribed by Hayato Tsuji; Yasuyuki Ueda; Laurean Ilies; Eiichi Nakamura


Publisher
John Wiley and Sons
Year
2011
Weight
49 KB
Volume
42
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Abstract

The selectivity of the reaction is controlled by subtle steric and electronic effects.


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ChemInform Abstract: Stereo- and Regiose
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Stereo-and Regioselectivity in Asymmetric Synthesis of ฮฑ-Amino Substituted Benzocyclic Compounds. -The key steps in the synthesis of the title compounds (V), which are potentially useful pharmaceutical synthons, are stereoselective reduction of the imines (III) and regioselective C-N bond cleavage.