The oxidative cyclization of the thiosemicarbazones of 4-piperidones (2) furnished spiro piperidino-1,2,4-triazoles (3,4,5), while the pyrolysis of 5 led to spiro piperidinoaziridines (6). The new compounds were characterized by IR and 1 H NMR spectral data.
โฆ LIBER โฆ
ChemInform Abstract: Synthesis of Some Spiro Piperidino-1,2,4-triazolidines and Aziridines.
โ Scribed by D. Bhaskar Reddy; A. Somasekhar Reddy; A. Padmaja
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Synthesis of Some Spiro
Piperidino-1,2,4-triazolidines and Aziridines. -The oxidative cyclization of thiosemicarbazones of 4-piperidones (III) (10 examples) provides a facile access to spiro(piperidine-triazoles) (IV)-(VI). Pyrolysis of spiro(piperidine-triazoles) (VI) results in a syn-elimination of nitrogen furnishing the spiro(piperidine-aziridines) (VII). -(REDDY, D.
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