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ChemInform Abstract: Synthesis of Some Spiro Piperidino-1,2,4-triazolidines and Aziridines.

โœ Scribed by D. Bhaskar Reddy; A. Somasekhar Reddy; A. Padmaja


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Synthesis of Some Spiro

Piperidino-1,2,4-triazolidines and Aziridines. -The oxidative cyclization of thiosemicarbazones of 4-piperidones (III) (10 examples) provides a facile access to spiro(piperidine-triazoles) (IV)-(VI). Pyrolysis of spiro(piperidine-triazoles) (VI) results in a syn-elimination of nitrogen furnishing the spiro(piperidine-aziridines) (VII). -(REDDY, D.


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Synthesis of some spiro piperidino-1,2,4
โœ D. Bhaskar Reddy; A. Somasekhar Reddy; A. Padmaja ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 149 KB ๐Ÿ‘ 2 views

The oxidative cyclization of the thiosemicarbazones of 4-piperidones (2) furnished spiro piperidino-1,2,4-triazoles (3,4,5), while the pyrolysis of 5 led to spiro piperidinoaziridines (6). The new compounds were characterized by IR and 1 H NMR spectral data.