ChemInform Abstract: Synthesis of Some Cyclic and Acyclic Nucleoside Analogues Derived from 4-(Trifluoromethyl)pyrimidines.
β Scribed by Hatice Berber; Mustapha Soufyane; Catherine Mirand; Sylvie Schmidt; Anne-Marie Aubertin
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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Acyclic Analogues of Pyrimidine Nucleosides. Synthesis of 1-(2-Hydroxyethoxy)methyl-and 1-(4-Hydroxybutyl)-5-amino Derivatives of Uracil. -Reaction of 5-aminouracil derivatives (I) with 4-bromobutyl acetate (II) or chloromethoxyethyl benzoate (V) followed by deacylation affords the title uracil der