The synthesis of 3-(3-pyridyl)-2-azabicyclo[2.2.2]octane 1, a semi-rigid analog of anabasine, is reported. This compound is prepared via Lewis acid promoted imino Diels-Alder reaction of 3-pyridine bismethylcarbamate 7 with 1,3-cyclohexadiene to form the rigid azabicyclic backbone. A 6-chloropyridyl
ChemInform Abstract: Synthesis of Semi-Rigid Analogues of Anabasine.
β Scribed by S. W. SZCZEPANSKI; K. G. ANOUNA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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