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ChemInform Abstract: Synthesis of (S)-α-Methylaspartic Acid by Diastereoselective Alkylation of a Chiral 2-Cyanopropanoate.

✍ Scribed by C. CATIVIELA; M. D. DIAZ-DE-VILLEGAS; J. A. GALVEZ; Y. LAPENA


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
28
Category
Article
ISSN
0931-7597

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## Abstract An efficient highly diastereoselective synthesis of quaternary α‐trifluoromethyl amino acids (III) and (V) is developed via allylation of enantiopure imines of trifluoropyruvate (I).