ChemInform Abstract: Synthesis of Ro 25-8210 via an Enantioselective Oxazaborolidine- Catalyzed Reduction.
β Scribed by K. G. HULL; M. VISNICK; W. TAUTZ; A. SHEFFRON
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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Oxazaborolidine-Catalyzed Enantioselective Reduction of Cyclic meso-Imides. -It is found that several meso-imides can be reduced with high enantioselectivity by means of the oxazaborolidine shown in the scheme and subsequent ethanolysis or acetylation. By conversion to a benzenesulfonyllactam, it is
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