## Abstract Treatment of phenyl 2,3,6,2β²,3β²βpentaβ__O__βbenzoylβ1βthioβΞ²βDβlactoside (7) with BF~3~ in methyl pyruvate afforded the corresponding phenyl 4β²,6β²β__O__β[(__R__)β1β(methoxycarbonyl)ethylidene]β1βthioβΞ²βDβlactoside (9) in 91% yield. The latter was converted via bromide 10 into the corres
ChemInform Abstract: Synthesis of Pyruvated Saccharide Fragments Related to the Aggregation Factor of the Marine Sponge Microciona prolifera.
β Scribed by T. ZIEGLER
- Book ID
- 112023653
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 23 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0931-7597
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A proteoglycan-like aggregation factor from the marine sponge Microciona prolqera (MAF) mediates cell-cell recognition via a cell-binding and a self-association domain. After repetitive and prolonged treatment of MAF with g1ycopeptide-Nglycosidase (PNGase) the specific binding of MAF to homotypic ce
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