Adhesion of a Viral Envelope Protein to a Non-Self-Binding Domain of the Aggregation Factor in the Marine Sponge Microciona prolifera

Involvement of a highly polyvalent Glyca

Involvement of a highly polyvalent Glycan in the cell-binding of the aggregation factor from the marine sponge Microciona prolifera

✍ Gradimir N. Misevic; Max M. Burger 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 606 KB

A proteoglycan-like aggregation factor from the marine sponge Microciona prolqera (MAF) mediates cell-cell recognition via a cell-binding and a self-association domain. After repetitive and prolonged treatment of MAF with g1ycopeptide-Nglycosidase (PNGase) the specific binding of MAF to homotypic ce